HIV-1 cure strategy by means of proviral knock-out using CRISPR-Cas9 has been hampered by the emergence of viral resistance against the targeting guide RNA (gRNA).Here, we proposed multiple, concentrated gRNA attacks against HIV-1 regulatory genes to block viral escape.The T cell line were transduced with single and multiple gRNAs targeting HIV-1 t
Proper selection of electrode material with sensible scheme is definitely significant to dodge commercial obstacles of supercapacitors.This challenge has been addressed by engineering prototype symmetric supercapacitor (SSC) device fabricated with enhanced supercapacitive vanadium (V) oxide integrated multi-walled carbon nanotubes (MWCNTs) composit
The first application of laparoscopic liver surgery consisted of wedge liver biopsies or resection of peripheral lesions, mostly benign.More recently, reports of anatomic left and right hepatectomy have been seen in the literature.Expertise in some centers has evolved to such an extent that even living related donor hepatectomy has been performed.T
Digital heritage obtained by real and tangible heritage, is formed by computer material, such as images through passive systems or active systems, or other graphic material, such as blueprints.These computer materials possess and must preserve the same cultural, historical, aesthetic, scientific or ethnologic value as the buildings they come from.T